Georgetown Lombardi Visiting Professor and Grand Rounds Lecture Series Featuring David Robbins, PhD
“Targeting Colorectal Cancer with Wnt Inhibitors”
Presented by:
David Robbins, PhD
Professor, Oncology
METRO Program Co-Leader
Georgetown Lombardi Comprehensive Cancer Center
Sponsor: Dr. Louis Weiner
Developmental signaling pathways, such as those controlled by Wnt and Sonic Hedgehog (Shh), play pivotal roles in the initiation, progression, and chemotherapeutic resistance of many cancers. As such, their dysregulation affects the mortality and morbidity of large numbers of such patients. Despite being commonly studied, few therapeutic agents against these highly cancer-relevant signaling pathways are in clinical use.
Our current focus is on understanding the role Wnt signaling plays in colorectal cancer and the role Shh signaling plays in brain tumors. The ultimate goal of our work is to identify novel therapeutic agents for cancer patients harboring tumors dependent on these developmental signaling pathways. Thus, the work in our lab spans the spectrum from basic mechanism to preclinical/translational relevance.
Learn more at the Robbins Lab website.
Lecture Series Presented by Georgetown Lombardi Comprehensive Cancer Center