Lecture, Research
Dean’s Seminar Series featuring M. Celeste Simon, PhD – “Exploiting Metabolic Tumor ‘Neighborhoods’”
Dean’s Seminar Series
M. Celeste Simon, PhD
Scientific Director and Investigator, Abramson Family Cancer Research Institute
Associate Director-Shared Resources, Abramson Cancer Center
Arthur H. Rubenstein, MBBCh Professor, Department of Cell and Developmental Biology
University of Pennsylvania Perelman School of Medicine
Title & Abstract:
“Exploiting Metabolic Tumor ‘Neighborhoods’”
Our laboratory investigates responses to changes in oxygen availability, as well as cancer cell adaptations to microenvironmental stresses that significantly contribute to advanced disease. Solid tumors frequently develop areas subjected to hypoxia and growth factor/nutrient deprivation, due to vascular insufficiency. I will discuss how this influences tumor progression.