Center for Metabolomic Studies Seminar Series Featuring Joshua D. Rabinowitz MD, PhD
Presentation: “Metabolism Revisited”
Speaker: Joshua D. Rabinowitz MD, PhD
Professor of Chemistry
Lewis-Sigler Institute for Integrative Genomics
Ludwig Institute for Cancer Research
About the Speaker: Joshua Rabinowitz is a Professor of Chemistry & Integrative Genomics at Princeton University. He brings a quantitative, chemical perspective to the study of diet and metabolism. His research focuses on two broad questions: What is the quantitative flow (flux) through different metabolic pathways? How is this flux controlled? To address these questions, his lab develops innovative technologies that blend mass spectrometry, isotope tracers, and computational data integration. These technologies have been broadly applied to address major biomedical problems, including diabetes, infectious disease, and cancer. In the field of oncology, Dr. Rabinowitz contributed to the discovery of the cancer-causing metabolite, 2-hydroxyglutarate. More recently, his work found that lactate, classically considered a waste product, is actual a major circulating fuel.