Bhussry Seminar Series: “Understanding Bile Acid Biology Through Metabolomics”
Presentation: “Understanding Bile Acid Biology Through Metabolomics”
Speaker: Andrew David Patterson, PhD
Department of Veterinary and Biomedical Sciences
Center for Molecular Toxicology and Carcinogenesis
Department of Biochemistry and Molecular Biology
Penn State University
About the Speaker:
Patterson is the Smith Professor and Professor of Molecular Toxicology at the Pennsylvania State University, University Park, PA, and is the Scientific Director of Metabolomics. He holds joint
appointments in the Department of Veterinary and Biomedical Sciences and the Department of Biochemistry and Molecular Biology. He and his students, postdocs, and collaborators focus on understanding the host-metabolite-microbiota communication network—specifically how the manipulation of gut microbiota by diet and/or xenobiotics impacts host metabolites, their metabolism, and how these co-metabolites interact with host ligand-activated transcription factors. The lab employs a variety of tools, including NMR- and mass spectrometry-based metabolomics, genomics, and conventional and gnotobiotic transgenic mice, to facilitate its study of these pathways and understand their impact on human health and disease.
Sponsored by the Department of Biochemistry and Molecular & Cellular Biology